Top 10s of priorities for research

The final workshop of a Priority Setting Partnership (PSP) enables patients, carers and clinicians to agree the Top 10 priorities for future research. We have listed all of the Top 10s below. The dates in brackets are the year in which the Top 10 was published.

Whilst the JLA refers to each list as a Top 10, a few of the PSPs have not limited their list to exactly 10 priorities. To find out more about how each PSP arrived at their Top 10, please visit the The PSPs section of the website.

Regardless of their position, all of the unanswered questions for each PSP are important. Where provided by the PSP, further details of the 20-30 unanswered questions discussed at the final workshop are shown, including their ranking, an explanation of the uncertainty, and details of any existing research reviewed.

The agreement of a Top 10 marks the beginning of the next stage of work for a PSP. The research priorities need to be promoted to key groups such as research funders, researchers, patients and carers and the wider research community, and individual more specific research questions need to be developed from the priorities. The Guidebook contains more advice on how PSPs can formulate research questions and work with researchers and research funders.

NIHR is interested in funding research which addresses any of the PSP priorities through its ongoing call for research.

A

Acne (2014)

Adult Social Work (2018)

Advanced Heart Failure (2020)

Alcohol-related Liver Disease (2018)

Anaesthesia (Canada) (2019)

Anaesthesia and perioperative care (2015)

Asthma (2007)

Autism (2016)

Autosomal Dominant Polycystic Kidney Disease (priority setting in association with the JLA) (2021)

B

Bipolar (2016)

Bleeding Disorders (2018)

Blood Pressure in Pregnancy (2020)

Blood transfusion and blood donation (2018)

Breast Cancer Surgery (2022)

Broken bones in older people (2018)

Broken Bones of the Upper Limb in People over 50 (2018)

C

Cardiac Arrest (Canada) (2021)

Cardiomyopathy (2024)

Cavernoma (2015)

Cellulitis (2017)

Childhood disability (2014)

Childhood Neurological Conditions (2022)

Children's Cancer (2022)

Cleft Lip and Palate (2012)

Coeliac Disease (2018)

Colorectal Cancer (Germany) (2022)

Common Conditions Affecting the Hand and Wrist (2017)

Community Nursing (2021)

Complex Fractures (2021)

Concussion (Canada) (2023)

Congenital Diaphragmatic Hernia (Australia) (2024)

Congenital Heart Disease (2022)

Contraception (2017)

COPD Flare-ups (2021)

Critical Care Asia and Africa (2024)

Cystic Fibrosis (2017)

Cystic Fibrosis Research Priorities Refresh (priority setting in association with the JLA) (2022)

D

Degenerative Cervical Myelopathy (2020)

Dementia (2013)

Dementia (Canada) (2017)

Depression (2016)

Detecting Cancer Early (2019)

Developmental Childhood Stammering (2024)

Diabetes - Type 1 Diabetes Mellitus in Adults Refresh (2024)

Diabetes (type 1) (2011)

Diabetes (type 2) (2017)

Diabetes and Pregnancy (2020)

Dialysis (Canada) (priority setting in association with the JLA) (2014)

Digital Technology for Adolescents and Young Persons with Inflammatory Bowel Disease (2024)

Digital Technology for Mental Health (2018)

Dystrophic Epidermolysis Bullosa (Spain) (priority setting in association with the JLA) (2012)

E

Ear nose and throat - Aspects of balance (2011)

Early Hip and Knee Osteoarthritis (2016)

Eating Disorders (Australia) (priority setting in association with the JLA) (2021)

Eating Disorders (Canada) (priority setting in association with the JLA) (2018)

Eating disorders (Netherlands) (2016)

Eczema (2012)

Elbow Conditions (2021)

Electronic cigarettes (2019)

Emergency medicine (2017)

Emergency Medicine Refresh (priority setting in association with the JLA) (2022)

Endometriosis (2017)

Epilepsy (2022)

Epilepsy (Canada) (2021)

Epilepsy 2009 priority setting (priority setting in association with the JLA) (2009)

F

Fibromyalgia (Canada) (2017)

First Time Soft Tissue Knee Injuries (2023)

Foot and Ankle Surgery (2022)

Foot Health (2019)

Frailty (Canada) (2017)

G

Gorton Community (2024)

Greener Operations: Sustainable Perioperative Practice (2022)

H

Hair loss (2015)

Head and Neck Cancer (Alberta, Canada) (priority setting in association with the JLA) (2016)

Healthcare Associated Infections (priority setting in association with the JLA) (2019)

Heart Surgery (2019)

Hidradenitis suppurativa (2013)

Hip and knee replacement for osteoarthritis (2014)

Hyperacusis (2018)

Hyperemesis Gravidarum (2019)

Hyperhidrosis (2019)

Hypertension (Canada) (2016)

I

Idiopathic Intracranial Hypertension (2018)

Inflammatory bowel disease (2015)

Inflammatory Bowel Disease Research Priorities Project (Australia) (priority setting in association with the JLA) (2022)

Intensive care (2014)

Irritable bowel syndrome (2023)

J

Juvenile Idiopathic Arthritis (Netherlands) (2020)

K

Kidney cancer (Canada) (2015)

Kidney transplant (2016)

L

Learning Difficulties (Scotland) (2018)

Lichen Sclerosus (2018)

Life after Stroke (2011)

Liver Glycogen Storage Disease (International) (2019)

Living With and Beyond Cancer (2018)

Lyme disease (2012)

M

Major Trauma (International) (2023)

Managing Chronic Conditions in Irish Primary Care (2024)

ME/CFS (2022)

Medically Not Yet Explained Symptoms (2021)

Menopause (2024)

Mental Health in Children and Young People (2018)

Mesothelioma (2014)

Metastatic Breast Cancer (Canada) (2018)

Methods of Rapid Reviews (PRioRiTy III) (priority setting in association with the JLA) (2021)

Mild to moderate hearing loss (2015)

Miscarriage (2017)

Mitochondrial disease (2020)

Multiple Conditions in Later Life (2018)

Multiple sclerosis (2013)

Myeloma (Canada) (2022)

N

Neuro-oncology (2015)

Neurodevelopmental Disorders (Canada) (2017)

Non-alcohol-related Liver and Gallbladder Disorders (priority setting in association with the JLA) (2019)

Nutritional Screening and Malnutrition (2019)

O

Obstructive Sleep Apnea (Saskatchewan, Canada) (2022)

Occupational Therapy (2020)

Occupational Therapy for Musculoskeletal Conditions and Arthritis (Canada) (2023)

Oral and Dental Health (2018)

Outpatient Service Delivery (2024)

P

Paediatric Emergency Medicine (2024)

Paediatric Hospital Care (Canada) (2021)

Paediatric Intensive Care Nutrition (2022)

Paediatric Lower Limb Surgery (2019)

Palliative and end of life care (2015)

Pancreatic Cancer (Germany) (2020)

Pancreatitis (2022)

Parkinsons (2014)

Patient safety in primary care (2017)

Pediatric Cancer (Canada) (2022)

Pediatric Inflammatory Bowel Disease (Netherlands) (2023)

Pemphigus and Pemphigoid (2023)

Pernicious Anaemia (2021)

Pessary use for Prolapse (2017)

Physiotherapy (2018)

Post Mastectomy Breast Reconstruction (Canada) (2021)

Pressure ulcers (2013)

Preterm birth (2014)

Problematic Hip Replacement (2023)

Progressive Pulmonary Fibrosis (2022)

Prostate cancer (2010)

PROTECT PSP (Priorities for Future Research on Reducing and Stopping Psychiatric Medicines)

Psoriasis (2018)

Psoriatic Arthritis (2021)

Pulmonary Hypertension (Canada) (2022)

Q

Quality Use of Medicines in People Living with Dementia (Australia) (2022)

R

Rare Inherited Anaemias (2018)

Rare Musculoskeletal Diseases in Adulthood (2018)

Recruitment to Clinical Trials (PRioRiTy) (priority setting in association with the JLA) (2016)

Retention in Randomised Trials (PRioRiTy II) (priority setting in association with the JLA) (2019)

Revision Knee Replacement (2020)

S

Safe Care for Adults with Complex Health Needs (2019)

Schizophrenia (2011)

Scoliosis (2017)

Seniors' Health (Alberta, Canada) (2019)

Sepsis (2024)

Sexual Violence (2022)

Sight loss and vision (2013)

Skin Cancer Surgery (2022)

Smell and Taste Disorders (2022)

Social Care Research Wales - Care and Support of Older People (priority setting in association with the JLA) (2021)

Social Care Research Wales – Family Support Services (priority setting in association with the JLA) (2023)