Priority 9 from the Neurodevelopmental Disorders Canada PSP
| UNCERTAINTY: Which are the most effective pharmacological and non-pharmacological intervention(s) to reduce anxiety in individuals with neurodevelopmental disorders? (JLA PSP Priority 9) | |
|---|---|
| Overall ranking | 9 |
| JLA question ID | 0056/9 |
| Explanatory note | This question is aimed at identifying which treatments are best to improve anxiety. This question encompasses identifying which medication-based treatments and which non-medication options (e.g. cognitive behavioural therapy) work best. There was also an interest in how this applies to individuals of different ages and effective options for those in rural communities. |
| Evidence | Systematic reviews: 1) Therapist-supported Internet cognitive behavioural therapy for anxiety disorders in adults. Cochrane Database of Systematic Reviews 2016, Issue 3. Art. No.: CD011565.DOI: 10.1002/14651858.CD011565.pub2.; 2) Ipser JC, Wilson D, Akindipe TO, Sager C, Stein DJ. Pharmacotherapy for anxiety and comorbid alcohol use disorders. Cochrane Database of Systematic Reviews 2015, Issue 1. Art. No.: CD007505. DOI: 10.1002/14651858.CD007505.pub2.; 3)Wu H, Yu D, He Y, Wang J, Xiao Z, Li C. Morita therapy for anxiety disorders in adults. Cochrane Database of Systematic Reviews 2015, Issue 2. Art. No.: CD008619. DOI: 10.1002/14651858.CD008619.pub2.; 4) James AC, James G, Cowdrey FA, Soler A, Choke A. Cognitive behavioural therapy for anxiety disorders in children and adolescents. Cochrane Database of Systematic Reviews 2015, Issue 2. Art.No.: CD004690. DOI: 10.1002/14651858.CD004690.pub4.; 5)Ori R, Amos T, Bergman H, Soares-Weiser K, Ipser JC, Stein DJ. Augmentation of cognitive and behavioural therapies (CBT) with d-cycloserine for anxiety and related disorders. Cochrane Database of Systematic Reviews 2015, Issue 5. Art. No.: CD007803. DOI: 10.1002/14651858.CD007803.pub2. |
| Health Research Classification System category | Mental Health |
| Extra information provided by this PSP | |
|---|---|
| Original uncertainty examples | What can be done for a child/adult suffering anxiety linked to their disorder? ~ What work can be done to catch anxiety early before it becomes part of the disability and interferes with daily living? ~ Are there non-pharmacological treatments for anxiety that work well? |
| Submitted by | Mostly family members/carers |
| PSP information | |
|---|---|
| PSP unique ID | 0056 |
| PSP name | Neurodevelopmental Disorders (Canada) |
| Total number of uncertainties identified by this PSP. | 63 (To see a full list of all uncertainties identified, please see the detailed spreadsheet held on the JLA website) |
| Date of priority setting workshop | 28 September 2017 |