Priority 16 from the Myeloma (Canada) PSP

UNCERTAINTY: How can we prevent and/or manage the neuropathy associated with myeloma and its treatment? (JLA PSP Priority 16)
Overall ranking	16
JLA question ID	0113/16
Explanatory note	Peripheral neuropathy can occur as a result of myeloma and its treatment. A common side-effect of myeloma treatment, neuropathy warranted its own indicative questions because it can also occur as a result of the disease (in the abence of treatment) and because of the volume of responses associated with it. Participants would like new ways to prevent, reduce, or manage neuropathy and new treatments that do not have this side-effect.
Evidence	No evidence identified
Health Research Classification System category	Cancer and neoplasms

Extra information provided by this PSP
Original uncertainty examples	chemo that was less prone to neuropathy ~ How to prevent and/or treat chemo driven peripheral neuropathy. ~ The biggest problem with current treatments is peripheral neuropathy. What is the best way to avoid this. ~ How can we stop the neuropathy that results from Chemo therapy? ~ Is there anything a patient can do to help alleviate the symptoms of neuropathy in the feet and hands. ~ Vitamin B supplementation to help with Peripheral Neuropathy? ~ Treatment of neuropathy, how to reduce it ~ Do vitamins really help decrease or prevent neuropathy?
Submitted by	Please see the PSP Engagement Summary on the JLA website

Extra information provided by this PSP

Original uncertainty examples

chemo that was less prone to neuropathy ~ How to prevent and/or treat chemo driven peripheral neuropathy. ~ The biggest problem with current treatments is peripheral neuropathy. What is the best way to avoid this. ~ How can we stop the neuropathy that results from Chemo therapy? ~ Is there anything a patient can do to help alleviate the symptoms of neuropathy in the feet and hands. ~ Vitamin B supplementation to help with Peripheral Neuropathy? ~ Treatment of neuropathy, how to reduce it ~ Do vitamins really help decrease or prevent neuropathy?

Submitted by

Please see the PSP Engagement Summary on the JLA website

PSP information
PSP unique ID	0113
PSP name	Myeloma (Canada)
Total number of uncertainties identified by this PSP.	59 (To see a full list of all uncertainties identified, please see the detailed spreadsheet held on the JLA website)
Date of priority setting workshop	28 April 2021