Priority 6 from the Multiple Sclerosis PSP
| UNCERTAINTY: Is vitamin D supplementation an effective disease modifying treatment for multiple sclerosis? (JLA PSP Priority 6) | |
|---|---|
| Overall ranking | 6 |
| JLA question ID | 0016/6 |
| Explanatory note | Existing relevant systematic reviews are not up-to-date |
| Evidence |
No evidence found |
| Systematic reviews that need extending or updating |
Jagannath VA, Fedorowicz Z, Asokan GV, Robak EW, Whamond L. Vitamin D for the management of multiple sclerosis. Cochrane Database of Systematic Reviews 2010, Issue 12. Art. No.: CD008422. DOI: 10.1002/14651858.CD008422.pub2. |
| Systematic reviews in preparation |
No reviews found |
| Ongoing controlled trials |
Vitamin D as add-on treatment for relapsing-remitting multiple sclerosis: an unicentric, randomized, double-blinded, placebo-controlled clinical trial? - VITADEM https://www.clinicaltrialsregister.eu/ctr-search/search?query=eudract_number:2012-004602-97 Efficacy of cholecalciferol (Vitamin D3) for delaying the diagnosis of MS after a clinically isolated syndrome D-Lay-MS NCT01817166 Vitamin D Supplementation in Multiple Sclerosis NCT01490502 |
| Health Research Classification System category | Neurological |
| Extra information provided by this PSP | |
|---|---|
| Original uncertainty examples | No examples provided. This is an indicative uncertainty and several submissions were merged to form this one. |
| Submitted by | 3 patients ~ 3 carers ~ 1 clinician |
| Outcomes to be measured | Management and or change of multiple sclerosis symptoms; adverse effects or complications; acceptability to patients or carers; time to return to work or normal activity; time in hospital and or needing health or social care services; health related quality of life; and costs. |
| PSP information | |
|---|---|
| PSP unique ID | 0016 |
| PSP name | Multiple Sclerosis |
| Total number of uncertainties identified by this PSP. | 82 (To see a full list of all uncertainties identified, please see the detailed spreadsheet held on the JLA website) |
| Date of priority setting workshop | July 2013 |