Priority 24 from the Mesothelioma PSP
| UNCERTAINTY: Should radiotherapy be given to mesothelioma patients at the incision site (as a result of surgery or thoracoscopy) to stop cancer cells spreading? (JLA PSP Priority 24) | |
|---|---|
| Overall ranking | 24 |
| JLA question ID | 0025/24 |
| Explanatory note | Not available for this PSP |
| Evidence | Systematic review - Lee C, Bayman N, Swindell R, Faivre-Finn C. Prophylactic radiotherapy to intervention sites in mesothelioma: a systematic review and survey of UK practice. Lung Cancer. 2009 Nov;66(2):150-6. doi: 10.1016/j.lungcan.2009.06.014. Epub 2009 Jul 23. Ongoing study - PIT: Prophylactic Irradiation of Tracts in Patients With Malignant Pleural Mesothelioma |
| Health Research Classification System category | Cancer |
| Extra information provided by this PSP | |
|---|---|
| Original uncertainty examples | Also I never had any treatment to the needle site despite being told it might happen. Is it needed or isn't it ~ Post VATS operation 3 days of radiotherapy to drain site, 7 minutes per session. Has there been a clinical trial to prove whether this is beneficial or not to the patient? Alan did experience seeding at the site despite the radiotherapy. |
| Comparison | None identified |
| Submitted by | Patient ~ bereaved |
| Outcomes to be measured | Prevention of metastases |
| PSP information | |
|---|---|
| PSP unique ID | 0025 |
| PSP name | Mesothelioma |
| Total number of uncertainties identified by this PSP. | 53 (To see a full list of all uncertainties identified, please see the detailed spreadsheet held on the JLA website) |
| Date of priority setting workshop | 16 December 2014 |