Priority 10 from the Mesothelioma PSP
| UNCERTAINTY: What, if any, are the benefits of pleurectomy (pleurectomy/decortication) compared to no surgery, and which mesothelioma patients might benefit? (JLA PSP Priority 10) | |
|---|---|
| Overall ranking | 10 |
| JLA question ID | 0025/10 |
| Explanatory note | Not available for this PSP |
| Evidence | Systematic review - Sestini S, Billè A, Okiror L, Gisabella M, Pastorino U. Systematic review on pleurectomy/decortication in the multimodality treatment of malignant pleural mesothelioma. Sestini S et al. Lung Cancer Management Vol. 3, No. 4, Pages 345-354 , DOI 10.2217/lmt.14.26. Ongoing study - MARS 2: A Feasibility Study Comparing (Extended) Pleurectomy Decortication Versus no Pleurectomy Decortication in Patients With Malignant Pleural Mesothelioma |
| Health Research Classification System category | Cancer |
| Extra information provided by this PSP | |
|---|---|
| Original uncertainty examples | Is there any indication of the efficiency of pleural decortication according to the stage of tumor at the time it is carried out? ~ Further studies are needed to find out whether Pleurectomy surgery is beneficial or not. ~ I also talked to people who have had operations to scrape the lung lining which has been successful is there any criteria for either of these treatments? |
| Comparison | None identified |
| Submitted by | Patient ~ Bereaved ~ Patient |
| Outcomes to be measured | Survival |
| PSP information | |
|---|---|
| PSP unique ID | 0025 |
| PSP name | Mesothelioma |
| Total number of uncertainties identified by this PSP. | 53 (To see a full list of all uncertainties identified, please see the detailed spreadsheet held on the JLA website) |
| Date of priority setting workshop | 16 December 2014 |