Priority 1 from the Juvenile Idiopathic Arthritis (Netherlands) PSP
| UNCERTAINTY: Pain and fatigue are often present when the disease is in remission. How does this happen, what can one do about it, and can one predict which patients will suffer from them? (JLA PSP Priority 1) | |
|---|---|
| Overall ranking | 1 |
| JLA question ID | 0094/1 |
| Explanatory note | This question asks about complaints (especially pain and fatigue) when the disease is in remission. Currently, it remains largely unknown why pain and fatigue occur when the disease is in remission and it results in a significant burden of disease. That is why this is an important question to address for the research community. |
| Evidence |
Systematic review - Pas R, et al. Hyperexcitability of the central nervous system in children with chronic pain. Pain Med 2018;19;2504-2514. |
| Health Research Classification System category | Inflammatory and immune system |
| Extra information provided by this PSP | |
|---|---|
| Original uncertainty examples | See data spreadsheet on JLA website |
| Submitted by | See data spreadsheet on JLA website |
| PSP information | |
|---|---|
| PSP unique ID | 0094 |
| PSP name | Juvenile Idiopathic Arthritis (Netherlands) |
| Total number of uncertainties identified by this PSP. | 53 (To see a full list of all uncertainties identified, please see the detailed spreadsheet held on the JLA website) |
| Date of priority setting workshop | 7 February 2020 |