Priority 18 from the Blood Pressure in Pregnancy PSP

UNCERTAINTY: What are the optimum blood pressure thresholds (for initiation) and targets for antenatal antihypertensive treatment? (JLA PSP Priority 18)
Overall ranking	18
JLA question ID	0099/18
Explanatory note	Not available for this PSP
Evidence	Chronic hypertension: effect of blood pressure control on pregnancy outcome.Panaitescu AM, Roberge S, Nicolaides KH.J Matern Fetal Neonatal Med. 2019 Mar;32(5):857-863. doi: 10.1080/14767058.2017.1390742. Epub 2017 Nov 1.PMID:28994336
Health Research Classification System category	Reproductive health and childbirth Cardiovascular

Extra information provided by this PSP
Original uncertainty examples	How high is too high ~ Is there a consistent safe level of high blood pressure for safety of mum and baby? ~ When should high blood pressure be regarded as high? ~ I am normally around 90 top value which went up to 130/140 and still wasn't viewed as an issue as it had to be 150 (which is incredibly high for me but may not be that high for someone who is normally 120/130. ~ Does early (before 20 weeks) control of blood pressure in pregnancy have benefits for the mother and baby, over and above controlling blood pressure later in pregnancy? ~ What is classed as a dangerous high blood pressure and can it be prevented What is the ideal blood pressure to aim for, and should I get a home monitor?
Submitted by	8 women, 9 healthcare, 1 researcher, 2 literature review of uncertainties reported

Extra information provided by this PSP

Original uncertainty examples

How high is too high ~ Is there a consistent safe level of high blood pressure for safety of mum and baby? ~ When should high blood pressure be regarded as high? ~ I am normally around 90 top value which went up to 130/140 and still wasn't viewed as an issue as it had to be 150 (which is incredibly high for me but may not be that high for someone who is normally 120/130. ~ Does early (before 20 weeks) control of blood pressure in pregnancy have benefits for the mother and baby, over and above controlling blood pressure later in pregnancy? ~ What is classed as a dangerous high blood pressure and can it be prevented What is the ideal blood pressure to aim for, and should I get a home monitor?

Submitted by

8 women, 9 healthcare, 1 researcher, 2 literature review of uncertainties reported

PSP information
PSP unique ID	0099
PSP name	Blood Pressure in Pregnancy
Total number of uncertainties identified by this PSP.	50 (To see a full list of all uncertainties identified, please see the detailed spreadsheet held on the JLA website)
Date of priority setting workshop	20 June 2019