Priority 16 from the Blood Pressure in Pregnancy PSP
| UNCERTAINTY: What are the fetal, infant and child outcomes in women taking antihypertensive agents? (JLA PSP Priority 16) | |
|---|---|
| Overall ranking | 16 |
| JLA question ID | 0099/16 |
| Explanatory note | Not available for this PSP |
| Evidence |
Impact of Antihypertensive Treatment on Maternal and Perinatal Outcomes in Pregnancy Complicated by Chronic Hypertension: A Systematic Review and Meta-Analysis.Webster LM, Conti-Ramsden F, Seed PT, Webb AJ, Nelson-Piercy C, Chappell LC.J Am Heart Assoc. 2017 May 17;6(5). pii: e005526. doi: 10.1161/JAHA.117.005526. Review.PMID:28515115 In-utero exposure to antihypertensive medication and neonatal and child health outcomes: a systematic review.Fitton CA, Steiner MFC, Aucott L, Pell JP, Mackay DF, Fleming M, McLay JS.J Hypertens. 2017 Nov;35(11):2123-2137. doi: 10.1097/HJH.0000000000001456. Review.PMID:28661961 Antihypertensive drug therapy for mild to moderate hypertension during pregnancy.Abalos E, Duley L, Steyn DW.Cochrane Database Syst Rev. 2014 Feb 6;(2):CD002252. doi: 10.1002/14651858.CD002252.pub3. Review. Update in: Cochrane Database Syst Rev. 2018 Oct 01;10:CD002252. PMID:24504933 |
| Health Research Classification System category | Reproductive health and childbirth Cardiovascular |
| Extra information provided by this PSP | |
|---|---|
| Original uncertainty examples | Are there any studies explaining what ranges of BP are associated with low birth weight or premature birth? ~ Drugs and outcomes to baby what are the best medications for controlling blood pressure in pregnancy, both for short term and longer term benefits for mother and baby? ~ What are the long term affects of the anti hypertensive medication on the baby? |
| Submitted by | 4 women, 3 healthcare, 2 researcher, 6 other |
| PSP information | |
|---|---|
| PSP unique ID | 0099 |
| PSP name | Blood Pressure in Pregnancy |
| Total number of uncertainties identified by this PSP. |
50 (To see a full list of all uncertainties identified, please see the detailed spreadsheet held on the JLA website) |
| Date of priority setting workshop | 20 June 2019 |