Priority 15 from the Autosomal Dominant Polycystic Kidney Disease Project
| UNCERTAINTY: Does early treatment of high blood pressure improve the long-term health of people with ADPKD and/or reduce the risk of thickened heart walls (left ventricular hypertrophy)? (Priority 15 | |
|---|---|
| Overall ranking | 15 |
| JLA question ID | 0103/15 |
| Explanatory note | Not available for this PSP |
| Evidence |
No evidence identified |
| Health Research Classification System category | Renal and urogenital |
| Extra information provided by this project | |
|---|---|
| Original uncertainty examples | How effective are Angiotensin converting enzyme inhibitors (ACEi) compared to Angiotensin Receptor Blockers (ARB), in people with ADPKD, for first-line treatment of blood pressure control? ~ What is the benefit of low blood pressure targets in people with early stage ADPKD or with left ventricular hypertrophy? ~ What are the benefits and harms of formal screening for hypertension in children with ADPKD; when benefits outweigh harms; at what age should screening be started in and what is the recommended frequency of screening? ~ What are the benefits and harms of detecting and treating prehypertension (BP 90-95th or even 75-95th percentile) in children with ADPKD? |
| Submitted by | Autosomal Dominant Polycystic Kidney Disease (ADPKD): Report from a Kidney Disease Improving Global Outcomes (KDIGO) Controversies Conference (.PDF) |
| Project information | |
|---|---|
| Project unique ID | 0103 |
| Project name | Autosomal Dominant Polycystic Kidney Disease |
| Total number of uncertainties identified by this project. |
35 (To see a full list of all uncertainties identified, please see the detailed spreadsheet held on the JLA website) |
| Date of priority setting workshop | 15 December 2020 |