Priority 13 from the Autosomal Dominant Polycystic Kidney Disease Project

UNCERTAINTY: What are the most effective treatments for high blood pressure (hypertension) for people (children and adults) with ADPKD? (Priority 13)
Overall ranking	13
JLA question ID	0103/13
Explanatory note	Not available for this PSP
Evidence	No evidence identified
Health Research Classification System category	Renal and urogenital

Extra information provided by this project
Original uncertainty examples	Which antihypertensive agents are most effective for hypertension in people with ADPKD? ~ Development of strategies to define second-line treatment agents for the management of hypertension in people with ADPKD. ~ What is the efficacy of aldosterone antagonists for the management of hypertension in people with ADPKD? ~ What is the impact, in people with ADPKD, of blood pressure control on kidney function?
Submitted by	Autosomal Dominant Polycystic Kidney Disease (ADPKD): Report from a Kidney Disease Improving Global Outcomes (KDIGO) Controversies Conference (.PDF)

Extra information provided by this project

Original uncertainty examples

Which antihypertensive agents are most effective for hypertension in people with ADPKD? ~ Development of strategies to define second-line treatment agents for the management of hypertension in people with ADPKD. ~ What is the efficacy of aldosterone antagonists for the management of hypertension in people with ADPKD? ~ What is the impact, in people with ADPKD, of blood pressure control on kidney function?

Submitted by

Autosomal Dominant Polycystic Kidney Disease (ADPKD): Report from a Kidney Disease Improving Global Outcomes (KDIGO) Controversies Conference (.PDF)

Project information
Project unique ID	0103
Project name	Autosomal Dominant Polycystic Kidney Disease
Total number of uncertainties identified by this project.	35 (To see a full list of all uncertainties identified, please see the detailed spreadsheet held on the JLA website)
Date of priority setting workshop	15 December 2020