Inflammatory Bowel Disease in Australia Question Verification Form

The purpose of this Question Verification Form is to enable Priority Setting Partnerships (PSPs) to describe clearly how they checked that their questions were unanswered, before starting the interim prioritisation stage of the process.

The JLA requires PSPs to be transparent and accountable in defining their own scope and evidence checking process. This will enable researchers and other stakeholders to understand how individual PSPs decided that their questions were unanswered, and any limitations of their evidence checking.

Name of the PSP

Inflammatory Bowel Disease in Australia Priority Setting JLA Lab

Please describe the scope of the PSP

The scope of the IBD RPP is defined as:

prevention
treatment
symptoms
diagnosis
living with IBD
inclusive of Crohn’s disease, ulcerative colitis and IBD unclassified
paediatric and adult.

The IBD RPP will exclude from its scope questions about:

microscopic colitis and other forms of inflammatory enteritis
cause
cure.

Please provide a brief overview of your approach to checking whether the questions were unanswered

Due to the broad scope of the priority setting, only high quality evidence (meta-analysis, systematic reviews and high quality guidelines) was included. A specific search was conducted for each of the 120 indicative questions to identify relevant and topic specific evidence. Specialist clinicians on the Steering Group were consulted regarding their specialised topic area, e.g., a dietitian recommended high quality studies and guidelines for indicative questions related to nutrition and IBD.

Please list the type(s) of evidence you used to verify your questions as unanswered

The evidence used to verify the questions were unanswered or partially answered were as follows:

meta-analysis
systematic reviews
IBD clinical guidelines

Please list the sources that you searched in order to identify that evidence

The sources used to verify the questions were unanswered or partially answered were as follows:

PubMed
The Cochrane Library
Gastroenterology Journal
APT Journal
Nature Reviews Journal
Cumulative Index to Nursing and Allied Health Literature (CINAHL)
PsychInfo
The Gastroenterological Society of Australia (GESA) guidelines
European Crohn's and Colitis Organisation (ECCO) guidelines
National Institute for Health and Care Excellence (NICE) guidelines
The British Society of Gastroenterology (BSG) guidelines
The European Society for Clinical Nutrition and Metabolism (ESPEN) guidelines
The European Society for Paediatric Gastroenterology, Hepatology and Nutrition (ESPGHAN) guidelines
Uptodate website
Google

What search terms did you use?

"Crohn* Disease” OR “Ulcerative Colitis” OR “IBD” OR “Inflammatory Bowel Disease” AND (indicative question topic area, e.g., “mental health”)

Please describe the parameters of the search (eg time limits, excluded sources, country/language) and the rationale for any limitations

Eligibility criteria used for the inclusion of evidence was as follows:
• To ensure evidence was recent, searches were restricted to the last 5 years (2016 onwards).
• Evidence searches were restricted to English language.
• Evidence searches were restricted to tier 1 journals only.
• Evidence searches excluded case reports and animal models.

Names of individuals who undertook the evidence checking

Dr Rimma Goldberg, Prof Paul Pavli, Dr Emma Halmos, Dr Ed Giles & Prof Antonina Mikocka-Walus

On what date was the question verification process completed?

16 September 2021

Any other relevant information

N/A